A new framework could help explain decades of conflicting hormone findings in ME/CFS and Long COVID

Reviewed by Dr Chris Armstrong, senior author and director of the Melbourne ME/CFS Collaboration, University of Melbourne. For decades, hormone studies in ME/CFS and Long COVID have produced conflicting results. A 2026 review led from the University of Melbourne offers a possible explanation: researchers may have been measuring the right system, but in the wrong […]
What if treatment didn’t have to be trial and error?
Earlier this week we shared MELOPIS, and what it’s starting to find about the brain in ME/CFS. Today, we want to take you inside a different piece of the program: TOTEM. For most people with ME/CFS, finding a treatment that works is trial and error. As Dr David Fineberg, GP and PhD candidate at the […]
Why the brain can’t “switch off” in ME/CFS
Research Update · Melbourne The brain that feels stuck is starting to show why Last week we shared a dispatch from Adelaide. This week, we’re back in Melbourne, with new findings from MELOPIS, and a call for the participants needed to finish it. MELOPIS investigates structural, neuro-vascular and biochemical differences in the brains of people […]
Results Are In: CTN Lite Patient & Caregiver Survey
In case you missed it, Open Medicine Foundation (OMF) has recently launched Clinical Trials Network (CTN) Lite—a streamlined research model enabling us to launch decentralised precision medicine treatment trials. The first step in launching this initiative? Get to know your priorities. Thanks to you, our community, we received 1,258 responses to our Patient & Caregiver […]
From the lab to the conference floor: OMF Australia at Converge 2026
Some weeks, the science is in the lab. Last week, it was on the conference floor in Adelaide, where OMF Australia sponsored Converge 2026, the Australian POTS Foundation’s annual conference. The Foundation does exceptional work within a community we share. Many people living with ME/CFS and Long COVID also live with POTS, MCAS, EDS and […]
From Cambridge: The OMF Team Comes Together for Research & Collaboration
Coming Together for Research & Collaboration At the end of May, Open Medicine Foundation’s Founder and CEO, CRC Directors, and VP of Research Programs all attended the 2026 Invest in ME Research Conference in Cambridge, UK. This annual event brings together researchers, clinicians, and advocates committed to advancing ME/CFS and Long COVID research worldwide. After […]
Inside SPOT-ME: paediatric ME/CFS research
Research in the youngest patients with ME/CFS Last week, we shared where the research is heading next. Today, we want to take you inside one of the projects already helping shape that future. Children and teenagers with ME/CFS have historically been almost invisible in biological research, despite being one of the two peak age groups […]
Where the science is leading next
Earlier this month, we marked ME/CFS Awareness Day with the community. Thank you for everything you do to help keep these diseases, and the people living with them, visible. Today, we want to share where the science is heading next, and why this moment matters. Watch the Video → After more than a decade of […]
Momentum into Outcomes: our 2025 Annual Report
As we close another year of progress toward effective treatments for ME/CFS and Long COVID, we want to share with you what your support has made possible Click the image to read the interactive e-zine. Thanks to the strength of the global OMF network and the leadership of Dr Chris Armstrong at the Melbourne ME/CFS […]
Today, we make ME/CFS visible
Show solidarity with the ME/CFS community on Awareness Day. Today, we make ME/CFS visible. On International ME/CFS Awareness Day, we honour the millions of people around the world living with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) — a serious, complex, and often invisible disease that continues to steal lives, families, careers, education, and futures. For many, […]